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Thursday, April 7, 2011

Cirrhosis - Hepatitis C


Cirrhosis is a progressive liver disease characterised by the replacement of healthy liver tissue with scar tissue (fibrosis), which can lead to liver failure. Hepatitis C is a viral infection that primarily affects the liver and can lead to cirrhosis over time if left untreated.

Relationship Between Hepatitis C and Cirrhosis:

  1. Chronic Infection: Hepatitis C can cause chronic liver inflammation, leading to liver damage and eventually cirrhosis in a significant number of cases.

  2. Progression: The progression from hepatitis C to cirrhosis can take decades, and not everyone with hepatitis C will develop cirrhosis. Factors such as alcohol use, obesity, and co-infection with other viruses can accelerate this progression.

  3. Symptoms of Cirrhosis: Symptoms may include fatigue, easy bruising, jaundice, swelling in the legs and abdomen, and confusion. Many people may remain asymptomatic until the cirrhosis is advanced.

  4. Diagnosis: Diagnosis can be made through blood tests for hepatitis C, imaging studies (like ultrasound), and liver biopsy or elastography to assess the extent of liver damage.

  5. Treatment: Direct-acting antiviral medications are very effective at curing hepatitis C, which can halt or even reverse liver damage in some patients. In advanced cases of cirrhosis, liver transplantation may be necessary.

Recommendations:

  • Regular Monitoring: Individuals with hepatitis C should have regular check-ups to monitor liver health.
  • Healthy Lifestyle: Avoiding alcohol, maintaining a healthy weight, and following medical advice can help manage liver health.
  • Vaccination: Vaccination for hepatitis A and B can benefit if there is liver disease.

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