Metformin - What DOCTORS don't tell you!

Metformin (brand names include Glucophage, Fortamet, Glumetza) is the most widely prescribed medication for Type 2 diabetes worldwide. It belongs to a class of drugs called biguanides.

Here is a comprehensive breakdown of what it is, how it works, and what you need to know if you are taking it.

1. Primary Uses

• Type 2 Diabetes: It is the first-line medication recommended for lowering blood sugar levels. It is often used alone or in combination with other drugs (like insulin).

• Prediabetes (Off-label): Doctors often prescribe it to prevent the progression from prediabetes to full Type 2 diabetes, particularly in people with a high BMI.

• Polycystic Ovary Syndrome (PCOS) (Off-label): It helps lower insulin levels and androgen (male hormone) levels, which can help regulate menstrual cycles and improve fertility/ovulation.

• Gestational Diabetes: Sometimes used during pregnancy when insulin is not an option or not preferred, though insulin remains the gold standard.

2. How It Works

Metformin does not increase the amount of insulin your body makes (so it rarely causes low blood sugar/hypoglycemia on its own). Instead, it works in three main ways:

1. Stops the Liver: It reduces the amount of sugar (glucose) your liver produces and releases into your bloodstream.

2. Boosts Sensitivity: It makes your muscle tissue more sensitive to insulin, allowing your cells to use glucose more effectively.

3. Reduces Absorption: It slightly decreases the amount of sugar your gut absorbs from the food you eat.

3. Side Effects

 

Common (The "Metformin Tummy"):

The most common complaints are digestive. These usually happen when you first start the drug and often go away after a few weeks.

• Diarrhea

• Nausea/Vomiting

• Stomach cramps/bloating

• Metallic taste in the mouth

Serious (Rare):

• Lactic Acidosis: A dangerous buildup of lactic acid in the blood. This is very rare (approx. 1 in 30,000 users) but can be fatal. Symptoms include extreme fatigue, muscle pain, difficulty breathing, and slow heart rate. It is mostly a risk for people with kidney or liver failure.

• Vitamin B12 Deficiency: Long-term use can block the absorption of Vitamin B12. Your doctor may monitor your levels periodically.

4. Important Warnings & Contraindications

• Kidney Function: Metformin is cleared by the kidneys. If you have severe kidney disease (typically eGFR < 30 mL/min), you cannot take it because it increases the risk of lactic acidosis.

• CT Scans/Contrast Dye: If you are having an imaging scan that uses iodinated contrast dye, you may need to stop taking Metformin for 48 hours before and after the procedure to protect your kidneys.

• Alcohol: Excessive alcohol intake (acute or chronic) drastically increases the risk of lactic acidosis.

• Liver Disease: Used with caution or avoided in severe liver disease.

5. Practical Tips for Success

If you have been prescribed Metformin, these strategies can help minimize side effects:

• Take with Food: Always take it in the middle of a meal or immediately after to buffer your stomach.

• Start Low, Go Slow: Doctors usually start you on a low dose (e.g., 500mg once daily) and slowly increase it over weeks. Do not rush this titration.

• Ask for Extended Release (XR/ER): If the standard "immediate release" tablets give you severe stomach upset, ask your doctor for the Extended Release version. It releases the drug slowly and is generally much gentler on the stomach.

6. Research on Longevity

You may hear Metformin discussed in "biohacking" or anti-aging circles. Some research suggests it might mimic the effects of calorie restriction and activate longevity pathways (like AMPK). However, there is currently no definitive clinical evidence that it extends lifespan in healthy humans, and it is not FDA-approved for anti-aging.

Common Non-Diabetic Causes of Foot Oedema (swelling)

 

Foot swelling can happen due to:

1. Long Standing or Sitting

Poor circulation can cause fluid to collect in the feet/ankles.

2. High Salt Intake

Excess salt makes your body retain water.

3. Medications

Some medicines may cause swelling (e.g., for blood pressure, pain, or hormones).

4. Kidney, Heart, or Liver Issues

These organs help regulate fluid balance. If not functioning well, swelling may appear.

5. Varicose Veins & Poor Venous Return

Weak vein valves cause blood pooling.

6. Foot/Ankle Injury

Sprains or soft-tissue injuries cause local swelling.

7. Infections or Skin Conditions

Especially if the area is red, hot, or painful.

General Safe Home Measures

These are mild, safe practices that often help relieve simple swelling:

1. Elevation

Raise your feet above heart level for 20–30 minutes, 2–3 times per day.

2. Reduce Salt Intake

Too much salt can worsen swelling. Eat less packaged/snack foods.

3. Gentle Movement

If you sit or stand for long hours:

• Walk for 5 minutes every hour

• Rotate ankles, flex toes, small exercises

4. Hydration

Drink enough water. Dehydration can paradoxically worsen swelling.

5. Compression Stockings

Only if advised by a doctor, especially if you have heart or circulation problems.

6. Check Your Shoes

Tight shoes can block circulation.

7. Cold Compress

For injury-related swelling use a cold pack for 10–15 minutes.

🌿 Alternative / Traditional Medicine Options

These can help mild cases but should not replace medical evaluation if swelling is persistent:

Ayurveda / Siddha

• Punarnava (Boerhavia diffusa) – commonly used for water retention

• Gokshura – supports urinary system

• Dashamoola decoctions – sometimes used for inflammation

• Mild herbal diuretics (only under practitioner supervision)

Acupuncture

May help circulation and reduce fluid buildup in some people.

Herbal Foot Soaks

• Warm water + Epsom salt

• Turmeric water soak (for mild inflammation)

❗ When You MUST See a Doctor

Seek medical care if you have:

• Swelling in both feet for more than 1–2 weeks

• Shortness of breath or chest discomfort

• Swelling with redness, heat, or pain (possible infection)

• Sudden swelling in one leg (risk of vein blockage)

• Swelling with kidney, heart, or liver symptoms

• You are on medication that may cause water retention

What Is Peripheral Neuropathy?

 

Peripheral neuropathy happens when the nerves outside the brain and spinal cord become damaged. These nerves control:

• Sensation (touch, pain, temperature)

• Movement

• Autonomic functions (digestion, heart rate, sweating)

🌟 ROOT CAUSES

1. Diabetes (Most Common Cause)

High blood sugar over time damages nerve fibers and blood vessels that supply the nerves.
If someone’s HbA1c is high (above 7), neuropathy risk increases sharply.

2. Vitamin Deficiencies

Especially:

• B12 deficiency

• B1, B6 deficiencies or excess

• Vitamin D deficiency

3. Poor Blood Circulation

Blood flow issues from:

• High cholesterol

• High blood pressure

• Smoking

• Vascular disease

4. Nerve Compression

From:

• Spine problems (disc bulge)

• Carpal tunnel syndrome

5. Autoimmune or Inflammatory Disorders

Examples: Guillain-Barré, lupus, rheumatoid arthritis.

6. Kidney or Liver Disease

Toxins accumulate and irritate nerves.

7. Medications or Alcohol

Some chemotherapy drugs and long-term alcohol use cause nerve damage.

8. Infections

Shingles, HIV, Lyme disease.

🩺 BEST REMEDIES (Scientific + Natural)

A. Manage the Root Cause

1. For diabetic neuropathy

This is critical:

• Aim for HbA1c below 7

• Reduce sugar, white flour, and rice portions

• Increase fibre and protein

• Walk 30–45 minutes daily

Good blood sugar control may slow, stop, or reverse early neuropathy

B. Vitamin Therapy

Do this only after a blood test, because taking B6 or B12 unnecessarily can cause nerve issues.

Usually beneficial:

• Methylcobalamin (B12) 1500 mcg/day (doctor-guided)

• Alpha Lipoic Acid (ALA) 600 mg/day (powerful for nerve repair)

• Vitamin D3 if low

C. Pain and Nerve Symptom Relief

Your doctor may recommend:

• Pregabalin

• Gabapentin

• Duloxetine
  These reduce burning, tingling, and electric-shock sensations.

🌿 AYURVEDA / SIDDHA REMEDIES (Supportive)

Ayurveda views neuropathy as Vata imbalance affecting nerve channels.

Herbal remedies

• Ashwagandha – Improves nerve healing, reduces stress inflammation

• Bala Thailam – External application

• Dhanwantharam 101 – For nerve strengthening

• Nerunjil and Aavarai – For diabetes control

• Turmeric + black pepper – Anti-inflammatory

Treatments

• Abhyanga (oil massage)

• Kizhi (herbal bundle therapy)

• Pizhichil

• Nasyam

These help nerve circulation and reduce pain.

Always go to a qualified Ayurvedic/Siddha physician for correct dosage and diagnosis.

🌿 1. SIDDHA (Traditional Tamil Medicine)

Siddha focuses on calming “Vatham” imbalance, which is linked to nerve issues.

⭐ What Siddha doctors usually do:

• Oil-based therapies
  Warm herbal oil application on feet to improve circulation and reduce burning.

• Herbal tonics
  Used to improve nerve strength and reduce inflammation (must be given by a qualified Siddha doctor).

• Diet plan
  Foods that calm Vatham like:
  – Warm foods
  – More vegetables
  – Less sugar and refined flour

👍 Good for:

• Burning sensation

• Tingling

• Nerve weakness

• Poor circulation

⚠️ Safety:

Never take Siddha internal medicines without a licensed practitioner—they can be strong.

💧 2. HOMEOPATHY

Homeopathy works on gentle nerve calming and whole-body balance.

⭐ Homeopathic practitioners often use remedies for:

• Burning feet

• Numbness

• Tingling

• Weakness

• Stress related to chronic illness

Homoeopathy is generally considered safe when prescribed by a trained homoeopathic doctor.

👍 Good for:

• Symptom relief

• Emotional stress

• Improving comfort

⚠️ Important:

Homoeopathic remedies should be chosen based on detailed symptoms, so it is best to avoid self-treatment.

🪡 3. ACUPUNCTURE

Acupuncture is one of the most effective alternative therapies for peripheral neuropathy.

⭐ How acupuncture helps:

• Improves blood flow to the nerves

• Reduces burning and tingling

• Supports nerve repair

• Helps balance blood sugar in some people

• Reduces foot pain

👍 Good for:

• Burning

• Tingling

• Numbness

• Foot weakness

⚠️ Important Safety Notes:

• It must be done only by a licensed acupuncturist

• Do NOT attempt any needle technique yourself

• It is safe even for young people, but always under professional supervision

🌟 BEST COMBINATION (Safe + Effective)

For many people, the following combination gives the best improvement:

✔ Acupuncture

(For nerve healing + pain relief)

✔ Siddha external therapies

(Oil massage, circulation improvement)

✔ Homoeopathic support

(Gentle relief for burning, tingling, emotional stress)

✔ Blood sugar control

(The key part: without this, nerve healing is slow)

🥦 FOOD FOR NERVE REPAIR

• Green leafy vegetables

• Nuts (almonds, walnuts)

• Seeds (chia, flax)

• Omega-3 (fish or flax oil)

• Turmeric

• Bitter vegetables (help control sugar)

Avoid:

• Sugar

• White bread/rice

• Excess tea/coffee

• Alcohol

• Smoking

🚶 PHYSICAL ACTIVITIES

• Brisk walking

• Foot exercises

• Yoga: Vajrasana, Trikonasana, Bhujangasana

• Gentle stretching

• Avoid prolonged sitting

⚠️ WHEN TO WORRY

Seek medical care urgently if:

• Rapidly worsening numbness

• Difficulty walking

• Weakness in feet/hands

• Loss of bladder/bowel control

• Sudden sharp pains

How to FIX Your Weak Erections DESPITE Diabetes or Insulin Resistance

 Weak erections associated with diabetes or insulin resistance are common due to the effects these conditions can have on blood flow, nerve function, and hormone levels. However, they can often be improved by addressing the root causes and implementing targeted treatments. Here’s a comprehensive guide to help:

1. Manage Blood Sugar Levels

• Why: Poorly controlled diabetes damages blood vessels and nerves, which are crucial for erections.
• How:
  • Follow a diabetic-friendly diet (low-glycemic foods, high in fibre, and healthy fats).
  • Monitor blood glucose levels regularly.
  • Use medications or insulin as prescribed by your doctor.
  • Exercise regularly to improve insulin sensitivity.

2. Improve Blood Flow

• Why: Erections depend on good circulation.
• How:
  • Exercise regularly (e.g., walking, cycling, or strength training).
  • Avoid smoking and reduce alcohol intake.
  • Stay hydrated.

3. Address Insulin Resistance

• Why: Insulin resistance contributes to hormonal imbalances and inflammation, both of which can impair erectile function.
• How:
  • Consider a low-carbohydrate or ketogenic diet to improve insulin sensitivity.
  • Use supplements like berberine, magnesium, or omega-3 fatty acids, as they may help improve metabolic health (consult your doctor first).

4. Optimize Hormone Levels

• Why: Low testosterone (common in diabetics) affects libido and erections.
• How:
  • Get your testosterone levels checked.
  • Incorporate zinc-rich foods, Vitamin D, and healthy fats to support testosterone production.
  • Consider testosterone replacement therapy if needed (under medical supervision).

5. Use Targeted Treatments for Erectile Dysfunction (ED)

• Options:
  • Phosphodiesterase-5 inhibitors (e.g., Viagra, Cialis): Help improve blood flow.
  • Vacuum erection devices: Enhance blood flow to the penis.
  • Penile injections or implants: For severe cases.
  • Shockwave therapy: May improve blood vessel function (consult a specialist).

6. Prioritize Nerve Health

• Why: Diabetes-related nerve damage (neuropathy) can impair erectile function.
• How:
  • Take alpha-lipoic acid or B vitamins (especially B12) to support nerve health.
  • Control your diabetes to prevent further nerve damage.

7. Manage Stress and Sleep

• Why: Stress and poor sleep increase cortisol levels, which can lower testosterone and impair sexual performance.
• How:
  • Practice stress-reducing techniques (e.g., meditation, yoga, deep breathing).
  • Aim for 7-9 hours of quality sleep per night.

8. Consider Psychological Factors

• Diabetes-related ED can sometimes be worsened by anxiety or depression.
• Seek counselling or therapy if psychological factors are contributing to your condition.

9. Consult a Specialist

• A urologist or endocrinologist can offer tailored solutions, including advanced therapies or procedures.

Lifestyle Summary

• Diet: Whole, unprocessed foods, low in refined sugars and carbs.
• Exercise: Aim for 150 minutes of moderate activity weekly.
• Habits: No smoking, limit alcohol, reduce stress.
• Medical: Regular check-ups to monitor diabetes and cardiovascular health.

By addressing these areas systematically, you can significantly improve your erectile function, even with diabetes or insulin resistance.

Changing the order of food can significantly impact blood sugar levels

 Changing the order in which you eat different types of food can significantly impact blood sugar levels, which is particularly important for managing diabetes mellitus. This approach leverages the concept of "food order" or "meal sequencing" to optimise glucose control. Here's how it works and why it can be effective:

Understanding Food Order and Blood Sugar Control

1. Carbohydrates Last: Consuming carbohydrates at the end of a meal can help reduce the spike in blood sugar levels. When eaten first, carbohydrates are quickly broken down into glucose, rapidly increasing blood sugar. By eating proteins, fats, and non-starchy vegetables first, glucose absorption is slowed down.
2. Protein and Fat First: Eating protein and fat can help slow gastric emptying and glucose absorption from carbohydrates consumed later, resulting in a more gradual increase in blood sugar levels.
3. Fiber and Vegetables: Eating high-fibre foods and non-starchy vegetables at the beginning of the meal can create a physical barrier in the stomach and intestines, further slowing down the digestion and absorption of carbohydrates.

Practical Steps to Implement Food Order Strategy

1. Begin with Vegetables and Protein:
• Start your meal with a salad or a serving of non-starchy vegetables such as leafy greens, broccoli, or bell peppers.
• Follow up with a portion of protein such as chicken, fish, tofu, or legumes.
2. Add Healthy Fats:
• Include healthy fats like avocados, nuts, seeds, or olive oil. These can be part of the salad dressing or a topping on your protein.
3. End with Carbohydrates:
• Finally, consume carbohydrates, such as whole grains, fruits, or starchy vegetables like sweet potatoes. This helps moderate the blood sugar response.

Scientific Support

Several studies have demonstrated the benefits of altering food order for blood glucose control:

• A study published in Diabetes Care (2015) found that consuming vegetables and protein before carbohydrates significantly reduced post-meal blood glucose levels in individuals with type 2 diabetes.
• Research in the journal BMJ Open Diabetes Research & Care (2020) showed that altering the food sequence in a meal could improve glycemic control and insulin sensitivity in people with type 2 diabetes.

Additional Tips for Managing Diabetes

1. Consistent Meal Timing: Eating at regular intervals can help maintain steady blood sugar levels.
2. Portion Control: Be mindful of portion sizes to avoid overeating, which can lead to blood sugar spikes.
3. Balanced Diet: Ensure your diet is well-balanced with various nutrients from different food groups.
4. Monitor Blood Sugar Levels: Regularly check your blood sugar levels to understand how different foods and meal sequences affect your glucose levels.
5. Consult a Healthcare Professional: Before making significant changes to your diet, it's advisable to consult with a healthcare provider or a registered dietitian, especially for personalised advice and monitoring.

Conclusion

Changing the order in which you consume different foods during a meal can be a practical and effective strategy to manage blood sugar levels in diabetes mellitus. By starting with vegetables and proteins and ending with carbohydrates, you can slow down glucose absorption and reduce post-meal blood sugar spikes, thereby aiding in better diabetes control.

---

References:

1. Diabetes Care 2015;38: E12-E14
2. BMJ Open Diabetes Research & Care 2020;8:e000896

 

Things you need to know about Neuropathy

 Neuropathy refers to damage or dysfunction of one or more nerves, typically in the peripheral nervous system (nerves outside the brain and spinal cord). This condition can lead to pain, tingling, numbness, weakness, and changes in sensation in the affected areas.

 Neuropathy can result from various causes, including:

Diabetes: Diabetic neuropathy is a common type of neuropathy that occurs in people with diabetes due to prolonged high blood sugar levels damaging the nerves.

Trauma: Physical injuries, such as from accidents, sports injuries, or surgeries, can damage nerves and lead to neuropathy.

Infections: Certain infections, such as shingles, HIV/AIDS, Lyme disease, and hepatitis C, can cause neuropathy.

Autoimmune diseases: Conditions like rheumatoid arthritis, lupus, and Guillain-Barré syndrome can trigger the immune system to attack the nerves.

Toxins: Exposure to toxins, such as heavy metals, chemotherapy drugs, or excessive alcohol consumption, can damage nerves and cause neuropathy.

Genetics: Some inherited disorders can lead to neuropathy, such as Charcot-Marie-Tooth disease.

Treatment for neuropathy aims to manage symptoms, prevent further nerve damage, and address the underlying cause when possible. Depending on the severity and type of neuropathy, treatment options may include:

 

Medications: Pain relievers, such as over-the-counter drugs (e.g., acetaminophen, ibuprofen) or prescription medications (e.g., gabapentin, pregabalin, duloxetine), may help alleviate neuropathic pain. In some cases, topical treatments or nerve blocks may be recommended.

Physical therapy: Exercises and stretches prescribed by a physical therapist can help improve strength, mobility, and coordination and reduce pain associated with neuropathy.

Lifestyle modifications: Managing underlying conditions, such as diabetes or autoimmune diseases, through proper diet, exercise, medication, and monitoring can help prevent further nerve damage. Avoiding activities or behaviours that exacerbate symptoms, such as smoking or excessive alcohol consumption, is also important.

Alternative therapies: Some individuals may relieve neuropathic symptoms through complementary and alternative approaches, such as acupuncture, massage therapy, biofeedback, or transcutaneous electrical nerve stimulation (TENS).

Nutritional supplements: Certain vitamins and minerals, such as B vitamins (e.g., B12), alpha-lipoic acid, and acetyl-L-carnitine, may have potential benefits for nerve health and neuropathic symptoms.

Surgery: In severe cases of neuropathy, particularly when compression of nerves or structural abnormalities contribute to symptoms, surgical interventions such as decompression surgery or nerve repair may be considered.

Individuals with neuropathy need to work closely with healthcare professionals, such as neurologists, primary care physicians, or pain management specialists, to develop a comprehensive treatment plan tailored to their specific needs and circumstances. Additionally, early diagnosis and intervention can help prevent or minimise complications associated with neuropathy.

Alternative medicine approaches may offer complementary options for managing neuropathy symptoms. However, it's important to note that these methods may not suit everyone, and evidence supporting their effectiveness can vary. Here are some alternative medicine options that individuals with neuropathy may consider:

 

Acupuncture: Acupuncture involves inserting thin needles into specific points on the body to stimulate nerve function, improve blood flow, and reduce pain. Some studies suggest that acupuncture may help alleviate neuropathic pain in specific individuals.

 

Acupressure: Similar to acupuncture, acupressure involves applying pressure to specific points on the body to promote healing and relieve pain. While research on acupressure specifically for neuropathy is limited, some people find it helpful for managing symptoms.

 

Herbal supplements: Certain herbs and plant extracts may have potential benefits for neuropathy symptoms. Examples include evening primrose oil, alpha-lipoic acid, capsaicin (from chili peppers), and ginkgo biloba. However, it's essential to consult with a healthcare provider before taking herbal supplements, as they may interact with medications or have side effects.

 

Massage therapy: Massage therapy can help improve circulation, reduce muscle tension, and alleviate pain associated with neuropathy. Gentle techniques, such as Swedish massage or reflexology, may particularly benefit individuals with neuropathy.

 

Yoga and tai chi: Mind-body practices like yoga and tai chi incorporate gentle movements, stretching, and relaxation techniques, which can help improve balance, flexibility, and overall well-being. Some studies suggest that yoga and tai chi help reduce neuropathic pain and improve quality of life in individuals with neuropathy.

 

Mindfulness meditation: Mindfulness-based practices, such as meditation and deep breathing exercises, can help reduce stress, promote relaxation, and enhance coping skills for managing neuropathy symptoms.

 

Dietary supplements: Certain vitamins and minerals, such as vitamin B12, vitamin D, magnesium, and omega-3 fatty acids, may support nerve health and function. However, it's essential to consult a healthcare provider before taking dietary supplements, as they may interact with medications or have side effects.

 

It's essentia to approach alternative medicine approaches for neuropathy as complementary to conventional treatments rather than replacements. Before trying any alternative therapies, individuals should consult with a healthcare provider to ensure they are safe and appropriate, especially if they have underlying medical conditions or are taking medications. Additionally, it's essential to continue following any prescribed treatment plans and regularly communicate with healthcare providers about symptoms and progress.

What are the Benefits of Stinging Nettle

Stinging nettle, scientifically known as Urtica dioica, is a perennial flowering plant that has been used for centuries due to its numerous health benefits. Despite its reputation for causing a painful sting when touched, stinging nettle offers a range of advantages when properly processed and utilized. From its rich nutrient profile to its potential therapeutic properties, here are some of the benefits associated with stinging nettle:

 

Nutritional Value: Stinging nettle is a nutrient powerhouse, containing an array of vitamins and minerals. It is particularly rich in vitamins A, C, and K, as well as iron, calcium, magnesium, and potassium. Including stinging nettle in your diet can help meet your daily nutritional requirements.

 

Anti-inflammatory Properties: Stinging nettle possesses anti-inflammatory properties that have been utilized in traditional medicine. It contains compounds like flavonoids and carotenoids that help reduce inflammation in the body. This makes it potentially beneficial for managing conditions such as arthritis, gout, and allergic reactions.

 

Allergy Relief: Stinging nettle has long been used as a natural remedy for allergies, especially hay fever. Research suggests that the plant can inhibit the production of histamine, a substance that triggers allergic reactions. Consuming stinging nettle or using it in the form of a herbal supplement may help alleviate symptoms like sneezing, itching, and nasal congestion.

 

Prostate Health: Extracts from stinging nettle root have been studied for their potential benefits in supporting prostate health. They may help reduce the symptoms of benign prostatic hyperplasia (BPH), a common condition characterized by an enlarged prostate gland. Stinging nettle extract can help improve urinary flow and alleviate discomfort associated with BPH.

 

Blood Sugar Control: Preliminary research suggests that stinging nettle may play a role in managing blood sugar levels. Some studies have shown that stinging nettle leaf extract can improve glucose metabolism and enhance insulin sensitivity. However, more research is needed to fully understand its effects on diabetes management.

 

Skin Health: Topical application of stinging nettle has been used to address various skin conditions. It can provide relief from itching, irritation, and inflammation associated with eczema, dermatitis, and insect bites. Stinging nettle extracts or creams can be applied directly to the affected area to soothe the skin and promote healing.

 

Rich in Antioxidants: Stinging nettle contains a variety of antioxidants, including flavonoids, phenolic compounds, and vitamin C. These antioxidants help neutralize harmful free radicals in the body, reducing oxidative stress and potentially lowering the risk of chronic diseases.

 

Detoxification Support: Stinging nettle has diuretic properties, meaning it promotes urine production and can aid in flushing out toxins from the body. It may support kidney function and help cleanse the urinary system, thereby contributing to overall detoxification.

 

Bone Health: The high mineral content of stinging nettle, including calcium, magnesium, and silica, makes it beneficial for maintaining strong and healthy bones. Regular consumption of stinging nettle, either in the form of tea or supplements, may help prevent osteoporosis and improve bone density.

 

Culinary and Culinary Uses: Stinging nettle can be used in various culinary preparations. Young nettle leaves can be blanched or steamed and used as a nutrient-rich ingredient in soups, stews, pesto, and teas. It offers a unique flavor profile and adds a nutritional boost to your meals.

 

Despite its potential benefits, it's important to note that stinging nettle may cause allergic reactions in some individuals. It is advisable to consult a healthcare professional before incorporating it into your diet or using it for medicinal purposes, especially if you have 

Metformin is a Anti-Aging Drug That Enhances Health span and Extends Lifespan

 Recent research suggests that metformin, a medicine used to treat type 2 diabetes, may have the ability to slow down the aging process by activating cellular pathways through AMPK that promote youthful cellular functioning, making it a promising candidate for an anti-aging drug. This is particularly good news for individuals with diabetes, as high blood glucose levels not only cause insulin resistance but also accelerate the aging process. Furthermore, studies have shown that metformin has benefits beyond regulating glucose levels and treating diabetes, including protection against cancer and cardiovascular disease, neuroprotection, and weight loss by regulating AMPK-activated pathways that promote healthy metabolism.

Is it possible that a commonly used medication for diabetes could also have anti-aging benefits?

Glycemic Index, and Insulin Index

Glycemic load and glycemic index are variables that measure the actual impact of foods that contain carbohydrates on blood glucose levels. The insulin index of a food demonstrates how much it elevates the concentration of insulin in the blood.

Despite efforts to control hyperglycemia, diabetes management is still challenging. This may be due to focusing on reducing hyperglycemia and neglecting the importance of hyperinsulinemia; while insulin resistance and resultant hyperinsulinemia preceded diabetes onset and may contribute to disease pathogenesis.

Glycemic index

The glycemic index is a tool that’s often used to promote better blood sugar management.

Several factors influence the glycemic index of a food, including its nutrient composition, cooking method, ripeness, and the amount of processing it has undergone.

The glycemic index can not only help increase your awareness of what you’re putting on your plate but also enhance weight loss, decrease your blood sugar levels, and reduce your cholesterol.

• Low: 55 or less
• Medium: 56-69
• High: 70 or higher

Insulin Index

The insulin index of a food represents the elevation of the insulin concentration in the blood during the 2-h period after the food is ingested. The insulin index represents a comparison of food portions with equal overall caloric content (250 kcal or 1000 kJ). The insulin index can be more useful than either the glycemic index or the glycemic load, because certain foods, such as lean meats, cause an insulin response despite the fact that they contain very low amounts of carbohydrates.  

The Glycemic Index Scale:

Selecting foods based on carbohydrate counting, glycemic index or glycemic load are common guides to control glycemia in diabetic patients, but neglect the insulin response, thus leading to failure in diabetes management. Therefore, paying attention to insulinemic response along with glycemic response seems to be more effective in managing diabetes.

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