Researchers have published details about how the first organisms on Earth could have become metabolically active. The results permit scientists to speculate how primitive cells learned to synthesize their organic components -- the molecules that form RNA, lipids and amino acids. The findings also suggest an order for the sequence of events that led to the origin of life.
A reconstruction of Earth's earliest ocean in the laboratory revealed the spontaneous occurrence of the chemical reactions used by modern cells to synthesize many of the crucial organic molecules of metabolism (bottom pathway). Whether and how the first enzymes adopted the metal-catalyzed reactions described by the scientists remain to be established.
Credit: Molecular Systems Biology / Creative
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