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Thursday, October 20, 2011

Men win humor test (by a hair)



 Psychology & Psychiatry 

 
Men just don't evolve. (winning caption); Oh, no, cavemen, is he going to eat me? (most often eliminated in the first round); In the tournament-style rating system used in the study, two captions were pitted against each other and participants chose the funnier. In this case, the top caption was the overall winner, and the bottom one was most often eliminated in the first round. Credit: © Mick Stevens/The New Yorker Collection/www.cartoonbank.com
Men are funnier than women, but only just barely and mostly to other men. So says a psychology study from the University of California, San Diego Division of Social Sciences.
While the findings support the stereotype on gender differences and humour – perhaps most vociferously and provocatively argued in recent memory by author Christopher Hitchens in his 2007 Vanity Fair article "Why Women Aren't Funny" – they also undermine the standard explanations as to why. The standard explanations are usually variations on an evolutionary sexual selection argument that likens a man's humor to a peacock's fancy tail or a deer's rack of antlers, useful primarily for showing off and impressing potential mates.
Besides, said the study's first author Laura Mickes, a postdoctoral researcher in the UC San Diego Department of Psychology and a Ph.D. graduate of the same department, "The differences we find between men's and women's ability to be funny are so small that they can't account for the strength of the belief in the stereotype."
Men edged out women by 0.11 points out of a theoretically possible perfect score of 5.0, while about 90 percent of both male and female study participants agreed with the stereotype that men are funnier.
The study, published in the journal Psychonomic Bulletin & Review, used a controlled version of The New Yorker cartoon caption contest to reach its conclusions.
Coauthors on the study are Nicholas Christenfeld, a UC San Diego professor of psychology, graduate students Drew Walker and Julian Parris, and Robert Mankoff, cartoon editor for The New Yorker.
Male prowess at the task of being funny on command, said Christenfeld, was "just at the edge of detectability," and men scored better with other men than with women.
The study team ran two separate but related experiments. The first experiment had 16 undergraduate males and 16 undergraduate females writing captions alone in a quiet room for 20 New Yorker cartoons in 45 minutes, for a total of 640 captions. All were instructed to be as funny as they could be.
Though writing captions may not be the most "natural" way to be funny, Christenfeld and Mickes explained, it has several distinct advantages, including a level playing field to determine what people are capable of doing (as opposed to what they do in social settings and day-to-day life, which could be governed by other factors). It also helps eliminate the effect of bias in the humor ratings since it is harder to tell, despite writer V.S. Naipaul's claims to the contrary, whether the writer is a man or a woman from written words alone.
The second phase of the first experiment had 34 male and 47 female undergraduates helping to rate the captions written earlier in a five-round knockout tournament: One cartoon image was displayed with two random and anonymous captions, and the raters chose the funnier of the two at their own pace. The process, with new captions each time, was repeated for all 32 captions for each cartoon. The 16 winning captions of round one were then randomly pitted against each other and so on. The number of rounds, from zero to five, that captions survived before being knocked out determined the writers' average scores.
True to the conventional wisdom, men did better than women, but not by much: Male writers earned an average 0.11 more points than female writers. But what's even more interesting, the researchers say, and what runs contrary to the standard explanations of why men might be funnier, is that men did better with other men: Female raters allocated only an average 0.06 more points to the male writers, while the male raters gave them a significantly higher average of 0.16 more points.
"Sad for the guys," Christenfeld said, "who think that by being funny they will impress the ladies, but really just impress other men who want to impress the ladies."
In a second, related experiment, the researchers tested memory and memory bias to see if men are credited with being funnier than they really are.
As expected, funny captions were remembered better than unfunny ones. The authors of funny captions were remembered better too. But humor was more often misremembered "as having sprung from men's minds," the researchers write. And, even more telling, Mickes said, when the study participants were guessing at authors' gender, unfunny captions were more often misattributed to women and funny captions were more often misattributed to men.*
So if the study is right and men are just a skosh more funny, why might that be? In analyzing the content of the captions, the researchers noted that men used profanity and sexual humor a little more frequently (about 4 vs. 2 percent of the time), but that didn't seem to account for the "win" since that style of caption didn't necessarily do better, with either sex.
It could be that men see more opportunities to take a stab at humor, said Christenfeld. It could be that they try harder or more often.
As The New Yorker cartoon editor Mankoff observed on his blog in May, after film critic Roger Ebert won the caption contest on his 107th try: Nine of the top 10 most devoted entrants, or "überenterers," are men. While fewer women win the actual contest, far fewer of them enter. When they do enter, though, their success rates are pretty impressive. Looking at contests #250 through #282, there are 32 winners, with 22 men and 10 women, Mankoff writes: "The 22 winning men entered an average of 70.22 contests, but the 10 women averaged 6.4 entries – and four of them won on their first attempt."
It remains for further research to ferret out the reasons men might be the marginally funnier sex. In the meanwhile, the current paper had one other finding worth noting: When asked to predict their own performance on a scale of one to five, the men figured they'd get a 2.3, and the women, a more modest 1.5. That is, the difference in self-assessment was greater than the actual difference detected by the contest. "Male confidence, in this domain at least," the researchers write, "does seem to outstrip male competence."
*Mickes declined to make any funny comments because they'd be attributed to her male coauthors anyway.
Provided by University of California - San Diego
"Men win humor test (by a hair)." October 19th, 2011. http://medicalxpress.com/news/2011-10-men-humor-hair.html
 
Posted by
Robert Karl Stonjek

X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus



 in Neuroscience 
Scientists at Cold Spring Harbor Laboratory (CSHL) have solved part of a puzzle concerning the relationship between changes in the strength of synapses – the tiny gaps across which nerve cells in the brain communicate – and dysfunctions in neural circuits that have been linked with drug addiction, mental retardation and other cognitive disorders.
A team led by CSHL Professor Linda Van Aelst has pieced together essential steps in a signaling cascade within excitatory nerve cells that explains a key phenomenon called longterm depression, or LTD. The "depression" in question has nothing to do with the human illness with that name. Rather, it refers to a tamping-down of the strength of individual synapses – what scientists call synaptic plasticity.
The mechanism behind LTD is called endocytosis. It involves a retraction of receptors where neurotransmitters can "dock." Van Aelst and colleagues have demonstrated how LTD works following activation of a class of receptors called group I metabotrobic glutamate receptors, or mGluRs.
It was known that longterm depression mediated by mGluRs depended in part on the rapid synthesis of specific proteins. Yet the identity of these proteins had largely remained a mystery. The CSHL scientists have now shown that locally rapid production of a protein called oligophrenin 1 (OPHN1) follows activation of group I mGluRs. OPHN1 in turn was shown to mediate LTD in hippocampal nerve cells, by interacting with yet another protein called EndophilinA2/3.
The result of this cascade of intracellular signals was dramatic: persistent removal of AMPA-type receptors at the excitatory synapse, and the onset of LTD. When rapid production of OPHN1 was blocked, mGluR-dependent LTD did not occur. These findings appear online today ahead of print in the journal Neuron.
Van Aelst explained the significance of the finding. "OPHN1 has two important functions that we know about. One is early in development, after synapses have appeared in the emerging nervous system. In this phase, OPHN1 in concert with other factors stabilizes receptors at synapses, and thus is essential in maintaining the structure of these essential features of neural circuitry.
"Our new findings show another vital role for OPHN1, later in development and into maturity. We assume that in response to behavioral stimuli – we aren't yet sure what kind – mGluRs are activated, setting off the series of steps that we identified: rapid upregulation of OPHN1, which binds to EndophilinA2/3, which in turn mediates the long-term removal of AMPA receptors."
OPHN1 is known to be associated with X-linked mental retardation and with other cognitive and behavioral deficits. The team hypothesizes that OPHN1-related changes in plasticity such as those described in their new work may be causally related to such pathology. They are investigating this possibility in their current work.
More information: "Rapid Synthesis of the X-linked Mental Retardation Protein OPHN1 Mediates mGluR-Dependent LTD through Interaction with the Endocytic Machinery" appears online ahead of print October 19 in Neuron
Provided by Cold Spring Harbor Laboratory
"X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus." October 19th, 2011.http://medicalxpress.com/news/2011-10-x-linked-mental-retardation-protein-synaptic.html
 

Posted by
Robert Karl Stonjek

Neuroscientists find normal brain communication in people who lack connections between right, left hemispheres



 in Neuroscience 
Neuroscientists find normal brain communication in people who lack connections between right, left hemispheres
 
(Top) Magnetic resonance images comparing a healthy subject (left) with an AgCC patient (right). The corpus callosum is the thick, 'c'-shaped structure outlined in the healthy brain and missing from the AgCC brain. (Bottom) Functional magnetic resonance images highlight symmetric patterns of synchronized activity in both healthy (left) and AgCC subjects (right) during rest with eyes closed. More than 15 of this type of network were found to be preserved in AgCC subjects. [Credit: California Institute of Technology]
(Medical Xpress) -- Like a bridge that spans a river to connect two major metropolises, the corpus callosum is the main conduit for information flowing between the left and right hemispheres of our brains. Now, neuroscientists at the California Institute of Technology (Caltech) have found that people who are born without that link—a condition called agenesis of the corpus callosum, or AgCC—still show remarkably normal communication across the gap between the two halves of their brains.
Their findings are outlined in a paper published October 19 in The Journal of Neuroscience.
Our brains are never truly at rest. Even when we daydream, there is a tremendous amount of communication happening between different areas in the brain. According to J. Michael Tyszka, lead author on the Journal of Neuroscience paper and associate director of the Caltech Brain Imaging Center, many areas of the brain display slowly varying patterns of activity that are similar to one another. The fact that these areas are synchronized has led many scientists to presume that they are all part of an interconnected network called a resting-state network. Much to their surprise, Tyszka and his team found that these resting-state networks look essentially normal in people with AgCC, despite the lack of connectivity.
“This was a real surprise," says Tyszka. "We expected to see a lot less coupling between the left and right brain in this group—after all, they are missing about 200 million connections that would normally be there. How do they manage to have normal communication between the left and right sides of the brain without the corpus callosum?”
The work used functional magnetic resonance imaging (fMRI) to demonstrate that synchronized activity between the left and right brain survives even this sort of radical rewiring of the nerve connections between the two hemispheres. The presence of symmetric patterns of activity in individuals born without a corpus callosum highlights the brain’s remarkable plasticity and ability to compensate, says coauthor Lynn Paul, research staff member and lecturer in psychology at Caltech. “It develops these fundamental networks even when the left and right hemispheres are structurally disconnected.”
The study that found the robust networks is part of an ongoing research program led by Paul, who has been studying AgCC for several decades. AgCC occurs in approximately one of every 4000 live births. The typical corpus callosum comprises almost 200 million axons—the connections between brain cells—and is the largest fiber bundle in the human brain. In AgCC, those fibers fail to cross the gap between the hemispheres during fetal development, forcing the two halves of the brain to communicate using more indirect and currently unknown means.
“In the 1960s and 1970s, Roger Sperry at Caltech studied 'split-brain' patients in whom the corpus callosum was surgically severed as a treatment for epilepsy," explains Paul. "Our research on AgCC has moved in a different direction and focuses on a naturally occurring brain malformation that occurs before birth. This allows us to examine how, and to what extent, the brain can compensate for the loss of the corpus callosum as a person grows to adulthood.”
According to the team, the findings are especially valuable in light of current theories that link impaired brain connections with clinical conditions including autism and schizophrenia.
“We are now examining AgCC subjects who are also on the autism spectrum, in order to gain insights about the role of brain connectivity in autism, as well as in healthy social interactions," says Tyszka. "About a third of people with AgCC also have autism, and altered connectivity in the corpus callosum has been found in autism. The remarkable compensation in brain functional networks that we found here may thus have important implications also for understanding the function of the brains of people with autism."
More information: "Intact bilateral resting-state networks in the absence of the corpus callosum," The Journal of Neuroscience.
Provided by California Institute of Technology
"Neuroscientists find normal brain communication in people who lack connections between right, left hemispheres." October 19th, 2011.http://medicalxpress.com/news/2011-10-neuroscientists-brain-people-lack-left.html
 

Posted by
Robert Karl Stonjek