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Monday, October 17, 2011

Small Nukes Get Boost


Nuclear Testing: This one-third scale test unit at Oregon State University allows researchers to measure the performance of NuScale’s reactor design. Steam is generated using electricity rather than nuclear reactions.
NuScale

COMPUTING

Small Nukes Get Boost

Fluor, the engineering giant, is investing $30 million to rescue the struggling startup NuScale.
  • SATURDAY, OCTOBER 15, 2011
  • BY KEVIN BULLIS
The large engineering and construction firm Fluor has taken a majority stake in NuScale Power, a startup that has been developing small, modular nuclear reactors. The investment effectively rescues NuScale, which had been near financial collapse after its biggest investor was indicted by the U.S. Securities and Exchange Commission for violating regulations.
The deal with Fluor will allow NuScale to continue its efforts to license its power plant design with the U.S. Nuclear Regulatory Commission, with the goal of having the first one up and running by 2020. Fluor's engineers will help with the certification work, and the company eventually plans to engineer and build NuScale's power plants.
The investment by Fluor is a vote of confidence in small modular nuclear reactors. These reactors generate 300 megawatts or less, about a third of what conventional nuclear reactors generate, and are designed to be safer and easier to manufacture. The technology has been gaining attention in recent years as high costs and safety concerns, such as those kindled by the nuclear accident at Fukushima, have hurt the prospects of large, conventional nuclear power plants. At the same time, organizations such as the International Atomic Energy Agency are anticipating a large market for small nuclear reactors in poor countries and in rural areas that don't have the infrastructure or demand to accommodate conventional large reactors.
Other major engineering and construction companies in the nuclear industry have recently shown support for small modular reactors, including Bechtel and Babcock & Wilcox, which this summer announced a partnership with the Tennessee Valley Authority to work toward building six of Babcock and Wilcox's small mPower reactors. Worldwide, dozens of designs being developed, including efforts in Japan, Korea, China, Russia, and Argentina.  U.S. Energy Secretary Steven Chu has made development and licensing of small modular reactors a focus for the U.S. Department of Energy.

The NuScale reactor design is based on technology developed by the DOE and Oregon State University, which was involved in the design and certification of the new Westinghouse AP1000 power plants that are being built now in China and at two locations in the United States. The reactor is a type of light water reactor, one of the most common types of reactors in use today. NuScale has completed a detailed preliminary design, and intends to submit a design certification application to the NRC next year.
NuScale's reactors are designed to generate 40 megawatts each, compared to over 1,000 megawatts for conventional reactors. They can be linked together on site to generate larger amounts of electricity. Traditionally, nuclear power plants have been built large to take advantage of economies of scale. But the large size of the projects leads to long construction times, and delays and cost overruns are common, heightening the risk for investors and increasing financing costs.
Smaller reactors, which can be built in factories rather than assembled on site, could be faster to build, lowering financing costs. The designs can also be simpler, and thus cheaper than conventional nuclear power plants, since the smaller reactors require lower pressures, for example, and their small size makes it practical to combine multiple elements into one containment vessel. Some experts have calculated that costs per megawatt could be comparable to large nuclear reactors, but no one really knows because no small, modular commercial nuclear power plants have been built yet.
Even if costs per megawatt prove higher than with conventional plants, their small size might make them attractive in areas that lack the power lines and other infrastructure needed to distribute power from a large reactor, and that may not immediately have demand for the full power output of a large reactor. The modular design could allow utilities to gradually add more reactors as demand increases. Several rural electric cooperatives in the United States have expressed interest in using NuScale's small nuclear reactors to replace aging coal plants—the small size of the plants would eliminate the need to upgrade existing transmission lines.
Critics of small nuclear reactors, such as the Union of Concerned Scientists, say that large numbers of small reactors could be more difficult to manage during an accident, and could pose greater risk of nuclear materials falling into the hands of terrorists or rogue states.

Faster-than-Light Neutrino Puzzle Claimed Solved by Special Relativity



The relativistic motion of clocks on board GPS satellites exactly accounts for the superluminal effect, says physicist.
KFC 
It's now been three weeks since the extraordinary news that neutrinos travelling between France and Italy had been clocked moving faster than light. The experiment, known as OPERA, found that the particles produced at CERN near Geneva arrived at the Gran Sasso Laboratory in Italy some 60 nanoseconds earlier than the speed of light allows.
The result has sent a ripple of excitement through the physics community. Since then, more than 80 papers have appeared on the arXiv attempting to debunk or explain the effect. It's fair to say, however, that the general feeling is that the OPERA team must have overlooked something.
Today, Ronald van Elburg at the University of Groningen in the Netherlands makes a convincing argument that he has found the error.
First, let's review the experiment, which is simple in concept: a measurement of distance and time.
The distance is straightforward. The location of neutrino production at CERN is fairly easy to measure using GPS. The position of the Gran Sasso Laboratory is harder to pin down because it sits under a kilometre-high mountain. Nevertheless, the OPERA team says it has nailed the distance of 730 km to within 20 cm or so.
The time of neutrino flight is harder to measure. The OPERA team says it can accurately gauge the instant when the neutrinos are created and the instant they are detected using clocks at each end.
But the tricky part is keeping the clocks at either end exactly synchronised. The team does this using GPS satellites, which each broadcast a highly accurate time signal from orbit some 20,000km overhead. That introduces a number of extra complications which the team has to take into account, such as the time of travel of the GPS signals to the ground.
But van Elburg says there is one effect that the OPERA team seems to have overlooked: the relativistic motion of the GPS clocks.
It's easy to think that the motion of the satellites is irrelevant. After all, the radio waves carrying the time signal must travel at the speed of light, regardless of the satellites' speed.
But there is an additional subtlety. Although the speed of light is does not depend on the the frame of reference, the time of flight does. In this case, there are two frames of reference: the experiment on the ground and the clocks in orbit. If these are moving relative to each other, then this needs to be factored in.
So what is the satellites' motion with respect to the OPERA experiment? These probes orbit from West to East in a plane inclined at 55 degrees to the equator. Significantly, that's roughly in line with the neutrino flight path. Their relative motion is then easy to calculate.
So from the point of view of a clock on board a GPS satellite, the positions of the neutrino source and detector are changing. "From the perspective of the clock, the detector is moving towards the source and consequently the distance travelled by the particles as observed from the clock is shorter," says van Elburg.
By this he means shorter than the distance measured in the reference frame on the ground.
The OPERA team overlooks this because it thinks of the clocks as on the ground not in orbit.
How big is this effect? Van Elburg calculates that it should cause the neutrinos to arrive 32 nanoseconds early. But this must be doubled because the same error occurs at each end of the experiment. So the total correction is 64 nanoseconds, almost exactly what the OPERA team observes.
That's impressive but it's not to say the problem is done and dusted. Peer review is an essential part of the scientific process and this argument must hold its own under scrutiny from the community at large and the OPERA team in particular.
If it stands up, this episode will be laden with irony. Far from breaking Einstein's theory of relatively, the faster-than-light measurement will turn out to be another confirmation of it.
Ref: arxiv.org/abs/1110.2685: Times Of Flight Between A Source And A Detector Observed From A GPS Satellite.

Tinkling of Bells



 


Lord Krishna“When They were crawling like that, They pleased Their mothers. The bells tied to Their waist and ankles sounded fascinating, and They would move around very pleasingly.” (Krishna, The Supreme Personality of Godhead
 
, Vol 1, Ch 8 )
The two luckiest women in the world, Mother Yashoda and Mother Rohini, made sure to care for their newfound bundles of joy, providing them the most wonderful ornaments, ensuring that the delights of Vrindavana
 
 would be all the more enchanting to everyone around. These two boys were already quite enthralling to begin with, but now that they were maturing, the care and attention paid to them by their mothers only increased. Correspondingly, the joy they returned to their parents only increased with the more attention that was paid to them.
Krishna and BalaramaWho were these two youths? The younger one was named Krishna because of His attractiveness and bluish complexion. Picture the dark raincloud that is about to pour down its nectar onto the crops that badly need it. Rain is not immediately appreciated by those looking to play outside or those hoping to avoid traffic on the roads. For the farmers, however, the rain is the necessary ingredient to maintain their way of life. Without the regular occurrence of showers, the crops could not be nourished, which would then leave the farmer without his source of income. More importantly, the food supply itself would be depleted. In this way, the young child's complexion was perfectly suited to His personality, for He would generously donate life-giving elixir to everyone who viewed Him with love and affection.
The dark clouds in the sky can appear blackish, and the ones about to pour rain have a bluish color mixed in. We’ve never seen anyone with this bodily complexion, but the statements of the sacred Vedic texts like theShrimad Bhagavatam
 
 and Mahabharata
 
 describe young Krishna’s appearance through this apt comparison. Photographic technology was not available five thousand years ago when the young Krishna roamed this earth. Neither are there any paintings that have been preserved from that time. Nevertheless, Krishna’s name and appearance are accepted as fact based on the statements of authority figures and those who delighted in His company. There are many things in life we haven’t witnessed personally, but if a trusted source describes them to us, we have no trouble accepting the information.
The elder son, the beloved of Mother Rohini, was fair in complexion. The two boys together thus resembled a raincloud coupled with a streak of lightning. They spent all of their time together as well. Though seemingly appearing from the wombs of different mothers in Vrindavana, Krishna and Balarama were really full brothers, sharing the same biological parents, Vasudeva and Devaki. Though this wasn't known to everyone in Vrindavana at the time, the two still spent all of their time together, thus being considered brothers by everyone regardless.
Mother Yashoda with Krishna and BalaramaThere are so many children appearing in different communities who also give delight to their parents and are given names which give pleasure to those who recite them. What then is so unique about Krishna and Balarama? Their divine natures are, of course, the reason for the attention given to them. That the person from whom everything emanates can descend to this temporary world and follow childish, sportive activities takes a lot of faith to accept, but the risk is well worth it. Shri Krishna is the very person we refer to as God; He is the Supreme Personality of Godhead.
Why the lengthy title? Why not just refer to Krishna as God? In the Vedic tradition, the Supreme Lord is described by His different features and also His relationship to the individual souls. Every life form we see is a spirit soul; they exist beyond the current lifetime. They existed prior to their current birth as well. The soul is eternal. It cannot be cut up, made dry, destroyed, or altered in properties.
The eternal soul is related to a more powerful soul, a supreme entity. Since the superior is also spirit in quality, He is referred to as Paramatma, or the supreme soul. God is supreme because He does not assume temporary bodies that become subject to the influence of nature. The living entity, the individual soul, requires a food source to remain in a particular form, but there is no such requirement for God. He can remain alive without any external source of energy, just like the sun, which, as a giver of heat and light, perpetually effuses its energy and doesn't ask anything in return.
Lord KrishnaThough the soul is not tied to its temporary body, it still has intelligence, bliss and eternality. This means that every soul is a personality, a person. The hands, legs, eyes and other features of the body are impersonal; they do not make up one’s identity. The atma, or soul, is the personality, the identifiable aspect. Similarly, the entire creation, including both the spiritual and material energies, does not directly represent the original Personality of Godhead. Since He is the Supreme Soul, He is also a person.
Since God does not limit Himself to just one spiritual manifestation, He is referred to as the Supreme Godhead. Combining the terms together, we get “Supreme Personality of Godhead”. This is an important address because many spiritual traditions purportedly following Vedic teachings refer to God as the “Supreme Formless Absolute Truth”. This is a dangerous title because if God is formless, He must accept forms when He comes to earth. If both the living entities and God accept material coverings and act undermaya's jurisdiction, they are essentially equal.
How can man be equal to God? Can man lift a giant hill with one finger and hold it up for seven consecutive days without breaking a sweat? We can't even go a few hours without eating, and yet somehow we are equal to God? Can man deliver the sublime wisdom of Vedanta philosophy at any second and to any person living in any time period? Can man create a giant land mass and compel it to float in space without any effort?
 
 can do all of these things because He is God and superior to the living entities. The devotees, those who understand that God is superior and meant to be loved, don't run into issues caused by bewilderment. Since they always call out the Lord's names found in the maha-mantra, "Hare Krishna Hare Krishna, Krishna Krishna, Hare Hare, Hare Rama Hare Rama, Rama Rama, Hare Hare
 
", they gain the favor of the Supreme Person. Just as the cow
 
 starts pouring milk when she hears her children crying, Krishna gives Himself to the devotee when they chant His name purely just once.
That's right. It takes just one utterance of the holy name without any motive for personal gain or personal satisfaction to become fully endeared to the Lord. Rather than just trust this principle as part of a theoretical analysis, we can look to the historical example of Krishna's playing in the holy land of Vrindavana to see practical evidence. Having descended to earth for many different reasons, Krishna gave pleasure to His foster mother while growing up in Vrindavana, which was a farm community.
Mother Yashoda loved Krishna with full affection, not even knowing His true identity. If she knew He was God, it might have checked her outpouring of love. Instead, she made sure her beloved child was treated just perfectly. Mother Rohini acted the same way towards Balarama, Krishna's brother. Krishna is the fountainhead of all forms of Godhead, and Balarama is the servitor God situated in the spiritual world always alongside the Lord, almost equal to Krishna.
Krishna and BalaramaAs young children not yet knowing how to walk, Krishna and Balarama had ankle bells put on by their mothers. For the bells to make noise, the two children had to move. Whenever the mothers would hear the bells tinkling, they would know that their beloved children were trying to crawl and walk. Thus they derived the most wonderful pleasure from hearing that sound and looking at their children.
When the heart is purified, where it leads the soul given to following it will also be pure. Mother Yashoda had not a hint of sin in her. She remains today the embodiment of chastity, virtue and motherly affection. Her caretaking of young Krishna is the model to follow for all parents, whose duty it is to see that their children grow up safe and protected and end up healthy and intelligent. Most important of all, the parent’s duty is to ensure that the child ends up being devoted to God.
Why is this last piece the most important? How can we ensure that anyone will like any particular thing? Fathers are known for wanting to have their sons grow up to be just like them only to be disappointed in the end. How can we force young children, who have their own natural tendencies, into surrendering unto the Supreme Lord? If we force, how can the resulting relationship be considered a loving one? Without pure love for Shyamasundara
 
, the sweetheart with a dark complexion, who wears a peacock feather in His hair, stands tall holding His flute in His soft hands, and whose smile defeats the pride of thousands of cupids, the aim of life is not met.
Lord KrishnaParents can’t force their children to become God conscious, but they can set up the environment where that end can be best achieved. It’s similar to how we ensure that our children get a good education and live in an environment conducive to acquiring knowledge so that they’ll grow up to be intelligent. We can’t actually do the homework for the children, for then they wouldn’t learn anything that way. The parents can create the proper surroundings, provide some encouragement, and see what happens from there.
Mother Yashoda’s example shows how to remain Krishna conscious yourself, which in turn rubs off on others. While she was working hard during the day, Yashoda would compose songs about the glorious pastimes of her beloved son and then sing them. She was a stay-at-home mom, but this didn’t mean that her life was empty or that she had nothing to do. Rather, the women in Vrindavana all worked very hard during the day - churning butter, taking care of the house, and sometimes even going into the city to sell their surplus supply of milk products. The gopis
 
, headed by Krishna’s beloved Shrimati Radharani
 
, were career women, except their occupations were aimed at satisfying the community and their family, not necessarily themselves. As Krishna was the heart of Vrindavana, everyone worked for Him.
Any parent who follows Mother Yashoda’s example of singing Krishna’s glories and tending to the Lord’s every need will be doing the greatest service for themselves and their family members. Though the Lord may not be in front of us directly, His name can rest within our heart and His deity
 
 can remain visible before our eyes. The heart’s business is to love, so when that prema is directed at Krishna, a pool of nectar soon appears. The mind that is given to bhakti-rasa, or devotional service
 
, can then swim in that pool, relishing the sweetness at every step. Someone who is perpetually in mental bliss will have the right attitude in life and thus be able to share their experiences with others. Mother Yashoda’s bliss came not only from thinking about Krishna, but from also hearing His wonderful ankle bells that tinkled as He moved here and there.
Krishna and BalaramaKrishna did not explicitly give Vrindavana tremendous opulence, knowledge of Vedanta, protection from being sent to hell, or any other reward not related to the foremost properties of the soul. He gave the residents pleasure, bliss and happiness not found through any other exchange. Krishna's pastimes were so wonderful that they thrilled anyone who heard about them. Moreover, descriptions of His childhood play give pleasure to people hearing about them today, many thousands of years after the fact.
The newspapers become outdated in terms of relevance very quickly. The information they contain is thus not very important. On the other hand, something as simple as crawling on the ground and jingling bells can continue to be heard about, learned from, and relished many thousands of years later. In this way the mercy of Krishna and Balarama can never be properly measured. Just sit back, enjoy, and make sure to never turn your back on the wonderful duo, who are the spiritual rainclouds pouring down the life-giving nectar to the devotees.
In Closing:
Mothers relish the charming bells as they tinkle,
Carefully wrapped were they around each ankle.
Their beloved Krishna and Balarama so precious,
In sacred land of their presence all are conscious.
Their every pastime proves to be supremely delightful,
For the onlookers, they hang on every move that is playful.
That these events took place in ancient times of no concern,
From play of Supreme Lord there is always much to learn.
Keep Krishna always in mind like did Yashoda the mother,
In providing bliss to the heart like Krishna there is no other.
Charming are He and His brother’s movements, even their sleep,
That divine vision of the duo in the mind always keep.

This chart is awesome! Everyone can use it.





    Apples
Protects your heart
Prevents constipation
Blocks diarrhea
Improves lung capacity
Cushions joints

Apricots
Combats cancer
Controls blood pressure
Saves your eyesight
Shields against Alzheimer's
Slows aging process

Artichokes
Aids digestion
Lowers cholesterol
Protects your heart
Stabilizes blood sugar
Guards against liver disease

Avocados
Battles diabetes
Lowers cholesterol
Helps stops strokes
Controls blood pressure
Smoothes skin

Bananas
Protects your heart
Quiets a cough
Strengthens bones
Controls blood pressure
Blocks diarrhea

Beans
Prevents constipation
Helps hemorrhoids
Lowers cholesterol
Combats cancer
Stabilizes blood sugar

Beets
Controls blood pressure
Combats cancer
Strengthens bones
Protects your heart
Aids weight loss

Blueberries
Combats cancer
Protects your heart
Stabilizes blood sugar
Boosts memory
Prevents constipation

Broccoli
Strengthens bones
Saves eyesight
Combats cancer
Protects your heart
Controls blood pressure

Cabbage
Combats cancer
Prevents constipation
Promotes weight loss
Protects your heart
Helps hemorrhoids

Cantaloupe
Saves eyesight
Controls blood pressure
Lowers cholesterol
Combats cancer
Supports immune system

Carrots
Saves eyesight
Protects your heart
Prevents constipation
Combats cancer
Promotes weight loss

Cauliflower
Protects against Prostate Cancer
Combats Breast Cancer
Strengthens bones
Banishes bruises
Guards against heart disease

Cherries
Protects your heart
Combats Cancer
Ends insomnia
Slows aging process
Shields against Alzheimer's

Chestnuts
Promotes weight loss
Protects your heart
Lowers cholesterol
Combats Cancer
Controls blood pressure

Chili peppers
Aids digestion
Soothes sore throat
Clears sinuses
Combats Cancer
Boosts immune system

Figs
Promotes weight loss
Helps stops strokes
Lowers cholesterol
Combats Cancer
Controls blood pressure

Fish
Protects your heart
Boosts memory
Protects your heart
Combats Cancer
Supports immune system

Flax
Aids digestion
Battles diabetes
Protects your heart
Improves mental health
Boosts immune system

Garlic
Lowers cholesterol
Controls blood pressure
Combats cancer
Kills bacteria
Fights fungus

Grapefruit
Protects against heart attacks
Promotes Weight loss
Helps stops strokes
Combats Prostate Cancer
Lowers cholesterol

Grapes
Saves eyesight
Conquers kidney stones
Combats cancer
Enhances blood flow
Protects your heart

Green tea
Combats cancer
Protects your heart
Helps stops strokes
Promotes Weight loss
Kills bacteria

Honey
Heals wounds
Aids digestion
Guards against ulcers
Increases energy
Fights allergies

Lemons
Combats cancer
Protects your heart
Controls blood pressure
Smoothes skin
Stops scurvy

Limes
Combats cancer
Protects your heart
Controls blood pressure
Smoothes skin
Stops scurvy

Mangoes
Combats cancer
Boosts memory
Regulates thyroid
Aids digestion
Shields against Alzheimer's

Mushrooms
Controls blood pressure
Lowers cholesterol
Kills bacteria
Combats cancer
Strengthens bones

Oats
Lowers cholesterol
Combats cancer
Battles diabetes
Prevents constipation
Smoothes skin

Olive oil
Protects your heart
Promotes Weight loss
Combats cancer
Battles diabetes
Smoothes skin

Onions
Reduce risk of heart attack
Combats cancer
Kills bacteria
Lowers cholesterol
Fights fungus

Oranges
Supports immune systems
Combats cancer
Protects your heart
Straightens respiration



 

Peaches
Prevents constipation
Combats cancer
Helps stops strokes
Aids digestion
Helps hemorrhoids

Peanuts
Protects against heart disease
Promotes Weight loss
Combats Prostate Cancer
Lowers cholesterol
Aggravates
Diverticulitis

Pineapple
Strengthens bones
Relieves colds
Aids digestion
Dissolves warts
Blocks diarrhea

Prunes
Slows aging process
Prevents constipation
Boosts memory
Lowers cholesterol
Protects against heart disease

Rice
Protects your heart
Battles diabetes
Conquers kidney stones
Combats cancer
Helps stops strokes

Strawberries
Combats cancer
Protects your heart
Boosts memory
Calms stress



 

Sweet potatoes
Saves your eyesight
Lifts mood
Combats cancer
Strengthens bones



 

Tomatoes
Protects prostate
Combats cancer
Lowers cholesterol
Protects your heart



 

Walnuts
Lowers cholesterol
Combats cancer
Boosts memory
Lifts mood
Protects against heart disease

Water
Promotes Weight loss
Combats cancer
Conquers kidney stones
Smoothes skin



 

Watermelon
Protects prostate
Promotes Weight loss
Lowers cholesterol
Helps stops strokes
Controls blood pressure

Wheat germ
Combats Colon Cancer
Prevents constipation
Lowers cholesterol
Helps stops strokes
Improves digestion

Wheat bran
Combats Colon Cancer
Prevents constipation
Lowers cholesterol
Helps stops strokes
Improves digestion

Yogurt
Guards against ulcers
Strengthens bones
Lowers cholesterol
Supports immune systems
Aids digestion 

Salt expands data storage


AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH   


Dr Joel Yang from the Institute of Materials Research and Engineering (IMRE), a research institute of Singapore’s Agency for Science, Technology and Research (A*STAR), with collaborators from the National University of Singapore (NUS) and the Data Storage Institute (DSI) has developed a process that can increase the data recording density of hard disks to 3.3 Terabit/in2, six times the recording density of current models. The key ingredient in the much enhanced patterning method that he pioneered is sodium chloride, the chemical grade of regular table salt. 

It’s like packing your clothes in your suitcase when you travel. The neater you pack them the more you can carry. In the same way, the team of scientists has used nanopatterning to closely pack more of the miniature structures that hold information in the form of bits, per unit area. Dr Joel Yang’s IMRE research team, working with peers from A*STAR’s DSI and NUS, has used nanopatterning to create uniform arrays of magnetic bits that can potentially store up to 3.3 Terabit/in2 of information, six times the recording density of current devices. This means that a hard disk drive that holds 1 Terabyte (TB) of data today could, in the future, hold 6 TB of information in the same size using this new technology.

Conventional hard disks have randomly distributed nanoscopic magnetic grains - with a few tens of grains used to form one bit – that enable the latest hard disk models to hold up to 0.5 Terabit/in2 of information. The IMRE-led team used the bit-patterned media approach, where magnetic islands are patterned in a regular fashion, with each single island able to store one bit of information.

“What we have shown is that bits can be patterned more densely together by reducing the number of processing steps”, said Dr Joel Yang, the IMRE scientist who heads the project. Current technology uses very tiny ‘grains’ of about 7-8 nm in size deposited on the surface of storage media. However, information or a single bit, is stored in a cluster of these ‘grains’ and not in any single ‘grain’. IMRE’s bits are about 10nm in size but store information in a single structure.

The method has been demonstrated to achieve data-storage capability at 1.9 Terabit/in2, though bits of up to 3.3 Terabit/in2 densities were fabricated. “In addition to making the bits, we demonstrated that they can be used to store data,” explained Dr Yang.

The secret of the research lies in the use of an extremely high-resolution e-beam lithography process that produces super fine nano-sized structures. Dr Yang discovered that by adding sodium chloride to a developer solution used in existing lithography processes, he was able to produce highly defined nanostructures down to 4.5 nm half pitch, without the need for expensive equipment upgrades. This ‘salty developer solution’ method was invented by Dr Yang when he was a graduate student at the Massachusetts Institute of Technology.

This work is the result of a collaborative effort with Prof Vivian Ng’s group at NUS, and Dr Yunjie Chen, Dr Siang Huei Leong, and Mr Tianli Huang from A*STAR DSI’s 10 Terabit/in2 Magnetic Recording programme.The researchers are now looking at increasing the storage density further.
Editor's Note: Original news release can be found here.

Hormone resistance: obesity



MONASH UNIVERSITY   

viviamo_-_measuring_tape_with_tablets
"Simply telling people to eat less and exercise more is not going to be sufficient to reverse the obesity trend."
Image: viviamo/iStockphoto
The effects of obesity - both on our bodies and on the health budget - are well known, and now, scientists are getting closer to understanding how the disease progresses, providing clues for future treatments.

In a study, published today in the prestigious journal Cell Metabolism, researchers at Monash University in collaboration with colleagues in the United States, have revealed how resistance to the hormone leptin, a key causal component of obesity, develops.

Lead author Professor Tony Tiganis, of the Monash Obesity and Diabetes Institute and Monash University's Department of Biochemistry and Molecular Biology, said our bodies produce leptin in response to increasing fat deposits. 

"Acting on a part of the brain called the hypothalamus, leptin instructs the body to increase energy expenditure and decrease food intake, and so helps us maintain a healthy body weight," said Professor Tiganis.

"The body’s response to leptin is diminished in overweight and obese individuals, giving rise to the concept of ‘leptin-resistance’. We've discovered more about how ‘leptin-resistance’ develops, providing new directions for research into possible treatments." 

Two proteins are already known to inhibit leptin in the brain and Professor Tiganis' team have discovered a third. In mice, this third protein becomes more abundant with weight-gain, exacerbating leptin-resistance and hastening progression to morbid obesity. The study showed that the three negative regulators of leptin take effect at different stages, shedding light on how obesity progresses. 

"Drugs targeting one of the negative regulators are already in clinical trials for Type 2 Diabetes, however, our research shows that in terms of increasing leptin-sensitivity in obesity, targeting only one of these won't be enough. All three regulators might need to be switched off," said Professor Tiganis.

The study showed that high fat diet-induced weight gain is largely prevented in genetically-modified mice when two of the negative regulators are deleted in the brain.

“We now have to determine what happens when all three negative regulators are neutralised. Do we prevent high fat diet-induced obesity?” 

Professor Tiganis said the more that is known about obesity, the better equipped scientists are to develop drugs to support good diet and exercise choices.

"Humans have a deep-seated attraction to overeating and nutrient-rich food, inherited from our hunter-gatherer ancestors. Now that food is more readily available and our lifestyles are less active, our evolutionary drive to overeat is becoming problematic."

More than four million Australians are obese and if current trends continue, by 2020, more than 80 per cent of adults and almost one third of children will be overweight or obese. Studies indicate that obesity and related health issues cost Australians more than $56 billion a year.

"Simply telling people to eat less and exercise more is not going to be sufficient to reverse the obesity trend. There is a pressing need to develop novel drugs that complement diet and exercise to both prevent and treat this disease," said Professor Tiganis.
Editor's Note: Original news release can be found here.

Diet determines drug dosage



THE UNIVERSITY OF SYDNEY   

MaRussya_-_broccoli_and_cauliflower
Cooking vegetables like cabbages, cauliflower and broccoli in curries can inhibit the enzyme CYP1A2. 
Image: MaRussya/iStockphoto
A University of Sydney PhD student has discovered the different diets and lifestyles of South Asians compared to Europeans could lead to the two groups requiring very different doses of medicines commonly used to treat illnesses such as depression and psychosis.

Vidya Perera, a final year PhD student in the Faculty of Pharmacy, has found that people from South Asia could need lower doses of these medicines because they are likely to have lower levels of CYP1A2, an enzyme that metabolises drugs.

"Vegetables such as cabbages, cauliflower and broccoli are known to increase levels of CYP1A2, as was demonstrated in this study and previous studies in people of European background. The lower levels of CYP1A2 in South Asians, however, appears to be due to the common practice of cooking these vegetables in curries using ingredients such as cumin and tumeric, ingredients known to inhibit the enzyme, overriding the effect of the vegetables," Mr Perera explained.

Mr Perera has just been declared the NSW winner of the AusBiotech/GlaxoSmithKline Student Excellence Awards as a result of his research.

"I started out looking for genetic differences between the two groups to account for the differences in CYP1A2 activity. What was fascinating to discover is that genetic differences only accounted for 3 per cent of variability in CYP1A2 activity, while environment and lifestyle factors accounted for 35 percent of the differences," Mr Perera said.

A total of 332 people took part in the study - 166 South Asians and 166 Europeans. CYP1A2 levels were measured by giving participants a caffeine tablet, and analysing CYP1A2 enzyme activity in saliva samples four hours later. Demographic, dietary and lifestyle information was obtained using a questionnaire.

"Most drugs are approved in clinical trials conducted in Europe and North America using healthy, middle-aged European men," Mr Perera explained. "This is the first study to look at CYP1A2 activity in South Asians. Understanding the correct dose of a medicine is crucial to achieving beneficial results and avoiding adverse drug reactions."

Professor Andrew McLachlan, Associate Dean (Research) in the Faculty of Pharmacy and Mr Perera's PhD supervisor, commented on the significance of this research.

"The development and testing of medicines is a global enterprise. The highest population growth is occurring in South Asia, yet we know relatively little about how to translate research findings between different populations of people."

"This research, for the first time, unpacks the complex interplay of factors that can affect how people breakdown and eliminate medicines from their body."

"Past research has attributed differences between people from different geographical regions to result from genetic differences. This important research highlights how dietary and cultural factors can impact on pharmacological response."

Mr Perera will travel to Adelaide this weekend to compete before a panel of judges in the national final of the AusBiotech/GlaxoSmithKline Student Excellence Awards. He will present his research on Sunday, with the winner to be announced on Monday.

AusBiotech 2011 is the annual conference of AusBiotech and the premier biotechnology and life sciences conference for Australia and the Asia-Pacific, attracting over 1400 delegates from across the world each year.
Editor's Note: Original news release can be found here.

How the ‘hospital superbug’ kills



MONASH UNIVERSITY   

monash_uni_-_clostridium
Transmission Electron Microscopy image of Clostridium difficile spores
Image: Monash University
An international team of scientists led by Monash University researchers has uncovered how a common hospital bacterium becomes a deadly superbug that kills increasing numbers of hospital patients worldwide.  The superbug accounts for an estimated $3.2 billion each year in health care costs in the United States alone.

In research published today in PLoS Pathogens, team leader Dr Dena Lyras and lead author Dr Glen Carter, from the Monash University School of Biomedical Sciences, demonstrate how a naturally occurring mutation in the bacterium Clostridium difficile causes potentially life-threatening diarrhoea in hospital patients undergoing antibiotic therapy.

Dr Lyras said C. difficile, which is able to colonise the colon when antibiotics, administered to treat other infections, have wiped out protective bacteria in the gut, causes a range of bowel disease symptoms, from mild diarrhoea to more chronic forms.

"We've found that particularly dangerous strains of C. difficile are produced when a mutation effectively wipes out an inbuilt disease regulator, called anti-sigma factor TcdC. Not only are these strains hypervirulent, they are resistant to broad spectrum antibiotics, making them difficult to treat," said Dr Lyras.

The results of the study suggest that all C.difficile strains carrying a similar mutation have the inherent potential to increase toxin production and become hypervirulent.

Dr Lyras said this increased understanding underlying infection severity was timely as the incidence of hospital acquired infections was rising.

"Over the past decade, there has been an astonishing increase in C.difficile infections throughout the world. Worryingly, the bacteria are also infecting people previously considered not at risk, including children and pregnant women.

"This is a major public health issue. Hospitals, intended as places of healing, provide the perfect environment for the rapid evolution of pathogens that target susceptible patients. 

"We must understand how these superbugs develop so we can develop treatments to combat them," added Dr Carter.

“This study gives us a better understanding of these strains - how they develop, how they cause disease and why they are so harmful - so we can design new strategies to prevent, control and treat the rising rates of infection."

Dr Lyras and Dr Carter collaborated with scientists from the Monash University Department of Microbiology and Monash Medical Centre, in Melbourne; the University of Glasgow, Kansas State University, and Institute Pasteur. The researchers were funded by the NHMRC, ARC, Wellcome Trust and NIH.
Editor's Note: Original news release can be found here.

New muscles for nanorobots



UNIVERSITY OF WOLLONGONG   
Uni_of_Wollongong_-_nanorobot_muscles
Image shows the tail region and insides of a futuristic microbot with the flagella-like tail, rotated by a length of the new carbon nanotube yarn torsional muscles.
Image: University of Wollongong
The possibility of a doctor using tiny robots in your body to diagnose and treat medical conditions is now one step closer to becoming reality thanks to research led by a team from the University of Wollongong.

The development of artificial muscles small and strong enough to push the tiny Nanobots along has just been published in the journal, Science.

Although Nanorobots (Nanobots) have received much attention for the potential medical use in the body, such as cancer fighting, drug delivery and parasite removal, one major hurdle in their development has been the issue of how to propel them along in the bloodstream.

An international collaborative team led by researchers at UOW’s Intelligent Polymer Research Institute (IPRI), part of the ARC Centre of Excellence for Electromaterials Science (ACES), has developed a new twisting artificial muscle that could be used for propelling nanobots.

The muscles use very tough and highly flexible yarns of carbon nanotubes (nanoscale cylinders of carbon), which are twist-spun into the required form. When voltage is applied, the yarns rotate up to 600 revolutions a minute, then rotate in reverse when the voltage is changed.

Due to their complexity, conventional motors are very difficult to miniaturise, making them unsuitable for use in nanorobotics.

“The twisting artificial muscles, on the other hand, are simple and inexpensive to construct either in very long, or in millimetre lengths,” according to ACES Chief Investigator, Professor Geoff Spinks.

“This new, giant, rotating type of actuation will open up lots of new opportunities for micro-machines,” he said.

Professor Spinks said the tiny artificial muscles can twist like those in the trunk of an elephant or the arm of an octopus.

“In these appendages, helically wound muscle fibres rotate by contracting against an incompressible, bone-less core. The rotation in the helically wound carbon nanotubes used for the twisting artificial muscles is caused by an increase of liquid electrolyte volume within the yarn, Professor Spinks said.

The research team working on this project includes Professor Spinks, Dr Javad Foroughi (Research Fellow with IPRI) and Professor Gordon Wallace (IPRI Director and the Executive Research Director of ACES). It also involves researchers from the University of Texas, Hanyang University and the University of British Columbia.

Professor Wallace said the exciting breakthrough has been made possible through the tremendous efforts of a team of multidisciplinary researchers working from four different countries over a sustained period of time.

“ACES continues to attract important collaborative research linkages with leading groups around the world and this is critical to maintain our position at the leading edge of scientific research,” Professor Wallace said.
Editor's Note: Original news release can be found here.

வெள்ளி ரதங்கள் அழகு மேகம்...(மகிழ்ச்சி)


வெள்ளி ரதங்கள் அழகு மேகம்...(மகிழ்ச்சி)

படம்: பருவ காலம்  (1974)
இயக்கம்: ஜோஸ் ஃபெர்னாண்டோ
நடிப்பு: கமல், பிரமிளா
இசை: தேவராஜன்
பாடியவர்: மாதுரி



http://www.divshare.com/download/13423607-101

ஆ ஆ ஆ ஆ ஆ ஆ ஆ ஆ

வெள்ளி ரதங்கள் அழகு மேகம்...

செல்லும் வீதி சிவந்த வானம் ...

பாவை நெஞ்சில் இளமை ராகம்...

பாட வந்தது பருவ காலம்...

வெள்ளி ரதங்கள் அழகு மேகம்...

செல்லும் வீதி சிவந்த வானம் ...

பாவை நெஞ்சில் இளமை ராகம்...

பாட வந்தது பருவ காலம்...

பருவ காலம்...பருவ காலம்...



பாடும் பறவை ஆயிரம் நடுவே...

நானும் ஒரு பறவை...

பாசம் பொழியும் உயிர்களுக்கெல்லாம்...

தந்தேன் எனதுறவை...

எங்கோ இருக்கும் மனிதர் யாரும்...

இங்கே வரவேண்டும்...

இனி எல்லா நலமும்...

எல்லா வளமும் எவரும் பெறவேண்டும்...

எவரும் பெறவேண்டும்...

ஹா ஹா ஹா ஹா ஹா ஆ ஆ ஆ ஆ ஆ ஆ

வெள்ளி ரதங்கள் அழகு மேகம்...

செல்லும் வீதி சிவந்த வானம் ...

பாவை நெஞ்சில் இளமை ராகம்...

பாட வந்தது பருவ காலம்...

பருவ காலம்...பருவ காலம்...



முல்லைக் கொடியும் என்னைப் பார்த்து...

சிந்தும் புன்னகையோ...

அலை மோதும் அருவி என்னைப் போலே

இளமைக் கன்னிகையோ...

அன்னை மடியில் பிள்ளை இருந்தால்...

அன்பு பெருகாதோ...

கொடி ஆசைக் கொண்டால் தழுவும் பூவின் உள்ளம் உருகாதோ..

உள்ளம் உருகாதோ..

ஹா ஹா ஹா ஹா ஹா ஆ ஆ ஆ ஆ ஆ ஆ

வெள்ளி ரதங்கள் அழகு மேகம்...

செல்லும் வீதி சிவந்த வானம் ...

பாவை நெஞ்சில் இளமை ராகம்...

பாட வந்தது பருவ காலம்...

பருவ காலம்...பருவ காலம்...

பருவ காலம்...


Read more: http://asokarajanandaraj.blogspot.com/2010/12/blog-post_1315.html#ixzz1b11ClHZM