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Thursday, May 28, 2015

EFFECT OF INSOLATION ON ‘777 OIL’ USED FOR PSORIASIS IN SIDDHA SYSTEM OF MEDICINE

Psoriasis (say "suh-RY-uh-sus") is a long-term (chronic) skin problem that causes skin cells to grow too quickly, resulting in thick, white, silvery, or red patches of skin.
Normally, skin cells grow gradually and flake off about every 4 weeks. New skin cells grow to replace the outer layers of the skin as they shed.
But in psoriasis , new skin cells move rapidly to the surface of the skin in days rather than weeks. They build up and form thick patches called plaques (say "plax"). The patches range in size from small to large. They most often appear on the knees, elbows, scalp, hands, feet, or lower back. Psoriasis is most common in adults. But children and teens can get it too.
Having psoriasis can be embarrassing, and many people, especially teens, avoid swimming and other situations where patches can show. But there are many types of treatment that can help keep psoriasis under control.
Experts believe that psoriasis occurs when the immune system overreacts, causing inflammation and flaking of skin. In some cases, psoriasis runs in families.
People with psoriasis often notice times when their skin gets worse. Things that can cause these flare-ups include a cold and dry climate, infections, stress, dry skin, and taking certain medicines.
Psoriasis isn't contagious. It can't be spread by touch from person to person.
Symptoms of psoriasis appear in different ways. Psoriasis can be mild, with small areas of rash. When psoriasis is moderate or severe, the skin gets inflamed with raised red areas topped with loose, silvery, scaling skin. If psoriasis is severe, the skin becomes itchy and tender. And sometimes large patches form and may be uncomfortable. The patches can join together and cover large areas of skin, such as the entire back.
In some people, psoriasis causes joints to become swollen, tender, and painful. This is called psoriatic arthritis (say "sor-ee-AT-ik ar-THRY-tus"). This arthritis can also affect the fingernails and toenails, causing the nails to pit, change color, and separate from the nail bed. Dead skin may build up under the nails.
Symptoms often disappear (go into remission), even without treatment, and then return (flare up).

777 Oil:


777 oil, a coded drug is used in the treatment of Psoriasis at Central Research Institute for Siddha, Madras (Krishnamurthy et al 1981). The oil is applied on the affected are of the skin and the patients are exposed to mild sunlight for a minimum period of 2 – 3 hours per day. This is repeated till a complete relief is obtained.


In the preparation of the drug, the fat soluble material of the leaves Wrightia trinctoria are extracted into the oil in sunlight. This method of preparation in sunlight is called “Sooriya pudam” in Siddha system of medicine. It is claimed that these fat soluble substances have Keratolytic action.
The role of sunlight both in preparation and treatment is particularly emphasised in this drug. In recent years Photochemotherapy and irradation with ultra – violet rays are tried in the treatment of Psoriasis with notable success (Skripkin, 1981).
777 oil is a single herbal formulation prepared by lipid extraction procedure. This drug is found to be effective in the management of Psoriasis. This formulation has already been clinically evaluated in several thousand of patients and has been proven to be effective for long term usage.
Indications
All types of Psoriasis, Dandruff, Fissure foot, Icthyosis, Fungal dermatosis, Ulcerative gingivitis, Apthous ulcers of mouth, First-degree burns.
Composition
Oil extracts of 

Wrightia tinctoria ( Swetha kutaja ) : 50% W/V
Oleum Cocos nucifera (Narikela )     : 50% W/V
Dosage/use
External use: Application after bath as a thin coating over affected surface. Exposure to morning sun for 15 mins after application. Use fingertips for application on scalp. Use Psorolin bathing bar and or Lumina shampoo for washing hair and body.
Contra indication
There is no known contra indication. Mild skin rashes in some cases are reported over the lesions at the beginning of the therapy .Such lesions will disappear within few days after regular use.

777 oil for psoriasis
Available in:
200ml $16.99
500ml $33.99
1000ml $63.99
“777 oil” is a code drug of the Siddha system of medicine used in the treatment of Psoriasis. The drug is derived from the leaves Wrightia tinctoria by insolation, with coconut oil as base. The present study is aimed at comparing the drug prepared by insolation with that prepared in darkness.
Analytical studies carried out in both the drugs showed difference in acid number without exposing to sunlight. The drugs showed changes in acid and iodine numbers on exposure to sunlight.
Studies on Thin Layer Chromatography showed no difference between the two drugs. However semi quantitative chromatography showed that two spots were more in concentration in the drug prepared in darkness than the drug processes in sunlight. Except one spot all the spots Rf values are identical to raw coconut oil.
In analytical studies carried out in shade dried leaves of Wrightia tinctoria showed the presence of iron calcium and ammonium. Alcohol had maximum extractive matter.